The period in history that involved Jews persecuted by Heraclius eventually resulted in a revolt around 625 AD where it can be found on the Biblical Timeline with World History. It was also a part of the long war between the Byzantine and Sasanian. According to scholars, the war hurt the population of Christians in Jerusalem and other areas such as the places near the east. The number of Christian deaths enabled the Arabs to invade the land. There were, however, some claims that no manuscripts or records in the past recorded the destruction of Christian communities situated in Jerusalem.
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The Byzantines frequently persecuted the Samaritans and Jews. The religious propaganda initiated by Byzantines featured information and images that were against the Jews. This caused the Jews to support the mission of Sasanians in their invasions. Several revolts were held such as the ones in Acre and Tyre, which were both in 610 AD. Unfortunately, some of the Jews were injured while others were massacred.
Persecutions of the Jews
During the year 622 BC Heraclius, a Roman Emperor, gathered his army to reclaim his territory that was taken by the Sasanians. Six years after, King Kavadh II of the Susanians intended to reconcile with Heraclius; however Kavadh II died after a short lived reign. In March 629, Heraclius entered Jerusalem (although there were some scholars who believed this was not the accurate date of his arrival because of some conflicts in the events that occured in history). There were claims that after Kavadh II died, there were six other people who ruled the empire including Shahrbaraz, Azarmidokht, Farrukh Hormizd, Ardashir II, Shapur-i Shahrvaraz and Borandukht.
Some scholars argue that it would have been impossible for Heraclius to reach Jerusalem during that time because the Persian troops were there. It would have been more likely for Heraclius to have waited till after Ardashir III was assassinated and Shahrbaraz ruled the Persian Empire in 630.
Heraclius and the Jews
The Jews decided to side with the Persians in the hopes of achieving better results than with the Byantines. By 611 AD, Judea and Syria were conquered by the Persians, and the army penetrated Jerusalem (much to the delight of the Jews). At this time, over 60,000 Christians were killed by the Persians and even the Holy Sepulcher was destroyed.
Unfortunately, it was too late when the Jews learned about the cruelty of the Persians. So, the Jews had a deal with Emperor Heraclius, which was intended to give him a better chance at reclaiming the Holy Land. When the bloody war between the Sasanians and Byzantines ended, Heraclius successfully reclaimed Judea. When the Jews tried to remind him of the promises he made to them, the emperor resisted and said that his victory was the result of his week of fasting and the will of God. Soon, he had all the Jews killed while those who were able to escape fled to Egypt for safety. This signaled the decline of Judaism in the land of Judea.
http://en.wikipedia.org/wiki/Jewish_revolt_against_Heraclius
http://en.wikipedia.org/wiki/History_of_the_Jews_in_the_Roman_Empire
https://www.jewishvirtuallibrary.org/jsource/biography/heraclius.html